Why you should consider intranasal drug administration as another option for delivering medications to patients:
Acute seizures, status epilepsy, heroin and narcotic overdose, insulin induced hypoglycemia, procedural sedation, and acute and chronic pain control are all complex medical problems requiring multiple approaches for effective management. Intranasal drug delivery is emerging as a low-tech, inexpensive and non-invasive first line method for managing selected patients with these and other medical problems. Nasal medication delivery takes a middle path between slow onset oral medications and invasive, highly skilled delivery of intravenous medications. Because the nasal mucosa is highly vascularized, delivery of a thin layer of medication across a broad surface area can result in rapid transmucosal absorption of the medication into the blood stream and cerebral spinal fluid. This results in therapeutic drug levels and effective treatment of seizures, pain, anxiety, hypoglycemia, opiate overdose, epistaxis (bloody noses), etc without the need to give a shot or a pill. Because intra-nasal medication delivery is effective using generic medications, it is quite inexpensive, an advantage in this era of increasingly expensive medical technology. This web site provides information in the form of medical research, expert testimonial opinion and protocol suggestions to health care providers and consumers regarding this emerging method of drug delivery.
Disclaimer: Most IN medications are off label and do not have FDA or other countries regulatory agency approved indications for intranasal delivery. Clinicians should use them based on patient needs and peer reviewed literature support realizing that many medical therapies and medication uses are used "off-label."